Friday, March 23

This afternoon, Charley's doctors called a parents meeting to inform us of the results of the bone marrow test. It was not good that the blast cells occupied 90% of the countable area in the marrow. It seems the chemotherapy only cleaned the blasts in the blood and helped Charley relieve some symptoms but failed in killing the leukemia in marrow. Therefore, Charley still suffers from persistent leukemia. There is a clinical trial may be available to Charley which includes a new drug, clolar, which the US FDA approved in 2004.

We appreciated friends in Singapore and Suzhou, China sharing their experiences of overcoming the failure of bone marrow transplant and achieving “precious” complete remission in bone marrow. The clinical trial Charley’s doctor intends to register requires normal liver, cardiac, and kidney functions, along with a clean CNS from leukemia. Charley has a higher Bilirubin level partially due to the treatment of peripheral nutrition. It could take up to a week. There is a risk that leukemia may attack again in this window of time while he will be examined by spinal fluid test and echo.

Charley’s appetite gradually comes back but nausea is still bothering him sometimes. Parents, grandmom and friends are busy in preparing his favorite dishes. The Shi family came to play with Charley today. Linda attended the parents meeting and gave us the support

-Deborah and Nehemiah

Prayer Request for Charley:
In addition to Linda’s prayer lists, please add:
* Charley’s Bilirubin recovers to the normal range
* No CNS metastasis
* The energy restores and immune system builds up in order to tolerate the Rx toxicities

2007年三月23号， 星期五

下午，田田的医生又与家长进行会谈，告诉我们骨髓检查的结果。结果不是很好，单位计数面积原始细胞占了90%。化疗好像只是清除了血液里的幼稚细胞，并缓解了一些肝脾和临床症状, 并没有杀死骨髓里的白血病细胞。因此，田田仍被診斷為高抗藥性白血病。美国有一個临床實驗可能適合田田 , 其中包括一種美国FDA在2004年通过的新药clolar,可能是对田田的情况有所帮助。

很感谢从新加坡和中国苏州的朋友分享他们在骨髓移植失败后获得明显缓解的宝贵经验。田田的医生打算进行的临床治疗方案需要田田的心、肝、肾功能良好，而且白血病没有侵犯中枢神经系统。目前田田的胆红素升高部分是由于肠外营养輸液引起, 雖已停用，胆红素降到要求，大概需五至六天。在等待骨髓和超声检查的空档期, 白血病有反复的可能。

田田食欲逐渐好转, 但仍有恶心。父母、佬佬和其他朋友都尽量为他准备适合口味的食物。石先生一家今天来看望田田，孩子們一起玩 legos。Linda也陪伴我們出席了今天的家长会，給予我们精神上很及時的扶持。她所寫的信(英文)表達了父母之心聲。

-Deborah and Nehemiah

请为田田祷告：
除了Linda的祷告内容外，加上：
* 希望田田的胆红素恢复正常
* 没有中枢神经系统的转移
* 恢复精力和免疫功能以能耐受药物的毒副作用